Naval Medical Research Unit (San Antonio, TX)

Naval Medical Research Unit (San Antonio, TX)

You must be a U.S. citizen in order to apply to the laboratory. No Dual Citizens will be considered for this facility.

NAMRU-SA’s mission is to conduct medical, craniofacial, and directed energy biomedical research, which focuses on ways to enhance the health, safety, performance, and operational readiness of Navy and Marine Corps personnel and addresses their emergent medical and oral/facial problems in routine and combat operations.

Combat Casualty Care and Operational Medicine

Expeditionary and Trauma Medicine Department

The Expeditionary and Trauma Medicine Department conducts RDT&E focused on the protection, resuscitation, and stabilization of combat casualties at frontline points of care in the combat theater. The Trauma medicine group focuses on primary and pre-clinical RDT&E for the development and optimization of drug products and advanced therapies for the treatment of hemorrhagic shock. The Expeditionary Medicine group works to identify and effectively mitigate stressors and improve survivability through the evaluation of products and agents that deliver capabilities to meet rapidly evolving expeditionary warfare requirements.

Cellular and Immune Based Adjuncts for Casualty Care Department

The Cellular and Immune Based Adjuncts for Casualty Care Department focuses on the evaluation of identification of biomarkers associated with wound healing, tissue and bone regeneration, and microbial infections, leveraging proteomic and transcriptomic data as we push towards personalized medicine. In addition, mechanistic and immunological profiles are established to identify potential therapeutic  targeting strategies to mitigate systemic and local effects that manifest in response to combat-related injuries. 

Biomedical Systems Engineering and Evaluation Department

The Biomedical Systems Engineering and Evaluation Department focuses on development of prototypic medical devices for treatment of combat injuries. Additionally, this department aims to create new or modify existing devices for field use in austere environments. Medical devices of interest range from sterilization equipment to devices to hemorrhage control.  Finally, the Evaluations group leads a large effort which is centered around test and evaluation of FDA approved medical devices. The main focus is test and evaluation of junctional and extremity tourniquets. Studies are initially completed using the Syndaver, or synthetic cadaver, and then frequently validated using military participants to evaluate effectiveness and other parameters such as ease of use.

Directed Energy Bioeffects and Human Systems Integration Department

The Bioeffects Program studies directed energy upon living systems and tissues. Directed energy sources including lasers are used extensively in the Navy are part of the next generation of weapons and counter-weapons systems. Current research efforts aim at evaluating the potential bioeffects associated with these systems aiding in establishment of exposure standards adequate to protect the health and safety of all personnel operating in and around these sources. The Human Systems Integration Program conducts research to generate and test computational models representing the physical interaction of all forms of directed energy with biological systems ranging from single cells to complex organisms. These models are used to estimate and understand the effects of new directed energy sources on biological, biomedical, or novel materials to include nanomaterials.

Craniofacial Health and Restorative Medicine

Epidemiology and Biostatistics Department

The Epidemiology and Biostatistics Department studies the distribution of oral, dental, and craniofacial diseases and injuries occurring in Sailors and Marines. Research is directed toward the improvement of diagnosis, treatment, and prevention of oral/dental diseases and injuries that affect the health and readiness of Sailors and Marines, while deployed or in garrison.

Maxillofacial Injury and Disease Department

The Maxillofacial Injury and Disease Department conducts research on the microbiology, immunology, etiology, diagnosis, and treatment of medical and dental diseases, especially infections and biofilms that are resistant to currently used antibiotics. Novel laser-acoustic methods and nanoparticle technologies are being studied to increase the armamentarium available to clinicians for the treatment of resistant infections.

Biomaterials and Environmental Surveillance Department

The Biomaterials and Environmental Surveillance Department conducts research, development, testing and evaluation of biomaterials used in medicine and dentistry. As the lead agent for mercury abatement in Navy Dental Treatment Facilities, the department is responsible for the development and testing of systems and technologies that minimize the environmental impact and occupational hazards of Navy Dentistry.

For information contact: Dr. William D'Angelo