Navy Medical Research Center
You must be a U.S. citizen to participate at this laboratory.
Program Dates: June 1, 2015 - August 7, 2015
Mission: To conduct research, development, tests and evaluations to enhance the health, safety and readiness of Navy and Marine Corps personnel in the effective performance of peacetime and contingency missions, and to perform such other functions or tasks as may be directed by higher authority.
The NMRC is composed of a number of Directorates:
- Infectious Diseases Research Directorate
- Biological Defense Research Directorate
- Combat Casualty Care Directorate
- Bone Marrow Research Directorate
- Research Services Directorate
- Administration Directorate
Infectious Diseases Research Directorate
The Infectious Diseases Research Directorate (IDD) conducts research on diseases that are considered to be significant threats to our deployed sailors, marines, soldiers and airmen. Significant are infectious diseases that have the potential to incapacitate a large number of deployed forces over a short time period thus hindering the ability of the warfighters to accomplish their mission. The geographical distribution of a disease; the lack of an effective vaccine, treatment or other control measures; the mode of transmission; and the historical impact during past wars are all factors that determine the importance of a disease to the US military.
Malaria Research Department: The primary objective of the Navy's malaria program is to develop vaccines that prevent malaria infection in military personnel.
Enteric Diseases Department: Research in the Enteric Diseases Department is focused on development of vaccines to prevent illness caused by Campylobacter and diarrheagenic E. coli.
Viral Diseases Department: Research efforts concerned with the development of an efficacious vaccine against dengue fever (an acute viral disease that is widely distributed throughout the tropical and sub-tropical areas of the world).
Rickettsial Diseases Department: Along with an entire series of rickettsiae, efforts focus primarily on Scrub Typhus, a disease of major military importance.
Infectious Disease Threat Assessment Department: The purpose of this research effort is twofold: 1) the systematic acquisition and assessment of infectious disease risk data from research projects and from collaborations with Navy CONUS and OCONUS medical treatment and research facilities for use in operational planning and research prioritization; and, 2) the development of prevention and control, diagnostic, and treatment strategies for infectious disease threats worldwide.
Biological Defense Research Directorate
The Biological Defense Research Directorate (BDRD) explores basic and applied microbiological, immunological and related scientific research methodologies for the development of medical diagnostics. Research personnel have designed, developed, and tested a broad variety of methodologies, which have allowed for swift and accurate disease diagnosis essential for substantive medical protection and readiness of Navy and Marine Corps personnel.
In addition, researchers have been instrumental in the advancement and refinement of confirmatory diagnostic methods utilizing polymerase chain reaction (PCR) methodologies in tandem with innovative, state of the art biosensor technologies.
Combat Casualty Care Directorate
The Combat Casualty Care Directorate (CCC) conducts basic and applied research aimed at understanding and developing interventions (prophylactics, therapeutics, guidances, devices, etc) that will improve the care of casualties or potential casualties sustained in combat and/or exposure to extreme environmental stressors of interest to the Navy and Marine Corps. The Directorate is subdivided into three Departments: (1) Resuscitative Medicine, (2) Diving & Environmental Physiology, and (3) Radiation and Combat Injury Repair.
Resuscitative Medicine: The Resuscitative Medicine Department conducts research on a variety of topics pertinent to the resuscitation of combat casualties, primarily those occurring in austere circumstances with anticipated delay to definitive care. Specific issues being explored contribute to the search for an optimal resuscitation fluid, prolongation of “the golden hour”, and the development of blood component substitutes.
- RMP-Metabolic Regulation - Decreased metabolism
- Hematomimetics - Blood Components Research for Hemorrhagic Shock
Diving & Environmental Physiology Department: This Department conducts research aimed at prevention and treatment of casualties incurred by exposure to extreme environmental stresses of operational interest, including undersea (submarine, diving, combat swimming), thermal (cold, hot), etc. This Department is engaged in three focused research efforts to meet these goals:
- Environmental Stress Program - Maintaining optimal human cognitive and physical performance levels in thermally extreme environments.
- Decompression Program - Understanding the mechanism of, and controlling the incidence of, decompression sickness
- Oxygen Toxicity Program - Preventing or reducing central nervous system and peripheral system toxicity associated with high pressure oxygen exposure
Radiation and Combat Injury Repair Department: This Department conducts research aimed at developing novel cellular interventions for casualties incurred by either conventional weaponry or from weapons of mass destruction (chemical agents or ionizing irradiation). This has two programs of research:
- Adult Stem Cell Expansion Program. This deprogram has developed a bone marrow culture system that stimulates the growth of primitive bone marrow cells called hematopoietic stem cells. These bone marrow stem cells can both self-regenerate and, when required, mature into each of the three major blood types.
- Composite Tissue Transplantation Program. This program looks at a most exciting new technology called “anergy therapy”. Using a rimate model, the scientists have demonstrated that this therapy prevents the rejection of mismatched organs and even full thickness skin following transplantation.
Bone Marrow Research Directorate
The Bone Marrow Research Directorate provides military contingency support for casualties with marrow toxic injury due to radiation or chemical warfare agents. The Directorate performs laboratory research, which supports technology innovations to make highly reliable and cost effective DNA-based typing for marrow transplants.
The Research Services Directorate consists of various departments, which provide research services to the other directorates at NMRC. These departments are listed below:
- Pathology Department
- Laboratory Animal Medicine and Science Department
- Clinical Diagnostics Department
- Technical Support Department
- Office of Research Administration
- Office of Technology Transfer
- Office of Intellectual Property
The Administration Directorate provides direction and support to the other Directorates and sets the policy required to ensure a coordinated effort in support of command requirements. Make recommendations to the Commanding Officer in areas regarding laws, regulations, policies, directives, and instructions pertaining to other naval organizations.
Subordinate Commands – NMRC is also responsible for the following commands, not located on site:
- NMRC Detachment - mission is to identify infectious disease threats of military relevance in Peru and surrounding countries in the South American region, and to determine the most effective means to assess, monitor, diagnose, prevent and treat these diseases to minimize their impact on the war fighter's operational capabilities.
- Naval Dental Research Institute - under the authority of the Bureau of Medicine and Surgery, the Naval Dental Research Institute conducts research, development, testing and evaluations that will limit disease, reduce dental emergencies, maximize operational readiness and promote the health, wellness and safety of military personnel.
- Naval Medical Research Unit 2 (NAMRU-2) Jakarta, Indonesia - mission of NAMRU-2 is to conduct research, development, tests and evaluations in infectious diseases to enhance the health safety and readiness of Navy and Marine Corps personnel in the effective performance of peacetime and contingency missions in Southeast Asia, and to perform other functions or tasks as may be directed.
- Naval Medical Research Unit 3 (NAMRU-3) Cairo, Egypt - NAMRU-3 conducts infectious disease research in support of Department of Defense (DoD) force health protection in the Middle East, Southwest Asia, Africa, and Eastern Europe.